Publications
2009
Park, J-H, von Maltzahn, G, Zhang, L, Derfus, AM, Simberg, D, Harris, TJ, Ruoslahti, E, Bhatia, SN, and Sailor, MJ (2009 in press): Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting. Small.
Higgins , J, Eddington, D , Bhatia, SN, Mahadevan, L (2009, in press): Statistical dynamics of flowing red blood cells by morphological image processing. PLoS Computational Biology.
Chen, AA[†], Khetani, SR[†], Lee, S, Bhatia, SN, Van Vliet, KJ (2009, in press): Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers. Biomaterials 30: 1113-1120. (PDF)
[†] These authors contributed equally
2008
Alvarez SD, Derfus, AM, Schwartz MP, Bhatia, SN, Sailor, MJ (2008): The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors. Biomaterials, 30: 26-34. (PDF)
Khetani, SR, Chen, AA, Ranscht, B,and Bhatia, SN(2008): T-cadherin modulates hepatocyte functions in vitro. FASEB Journal, 22:3678-3775. (PDF)
Park, J-H, von Maltzahn, G, Ruoslahti, E, Bhatia, SN, Sailor, MJ (2008): Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery. Angewandte Chemie,47: 7284-7288. (PDF)
Von Maltzahn, G, Ren, Y, Bhatia, SN (2008): In vivo tumor cell targeting with "click" nanoparticles. Bioconjugate Chemistry, 19:1570-1578. (PDF)
Harris, TJ, von Maltzahn, G, Lord, ME, Park, J-H, Agrawal, A, Min, D-H, Sailor, MJ, Bhatia, SN (2008): Protease-Triggered Unveiling of Bioactive Nanoparticles. Small, 4:1307-1312. (PDF)
Park, J-H, von Maltzahn, G, Schwartz, MP, Ruoslahti, E, Bhatia, SN, Sailor, MJ (2008, in press): Magnetic iron oxide nanoworms for tumor targeting and imaging. Advanced Materials. (PDF)
News article in Analytical Chemistry 'Analytical Currents' section: Improved superparamagnetic nanoparticles for targeting and imaging; Analytical Chemistry, July 1 2008, page 4777.(PDF)
Flaim CJ, Teng D, Chien S, and Bhatia, SN (2008). Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells and Development, 17: 1–11. (PDF)
Khetani, SR, and Bhatia, SN (2008): Microscale human liver tissue for drug development. Nature Biotechnology, 26 (1): 120-126. (PDF)
2007
Albrecht, DR, Underhill, GH, Mendelson, A, Bhatia, SN (2007). Multiphase electropatterning of cells and biomaterials. Lab on a Chip, 7: 702 – 709. (PDF)
von Maltzahn, G [†], Min, D-H [†], Zhang, Y, Park, J-H, Harris, TJ, Sailor, M, Bhatia, SN (2007): Nanoparticle self-assembly directed by antagonistic kinase and phosphatase activities. Advanced Materials, 19(21): 3579-3583. [†] These authors contributed equally
(PDF)
Underhill, GH and Bhatia, SN (2007): High-throughput analysis of signals regulating stem cell fate and function. Current Opinion in Chemical Biology, 11: 357-366 (PDF)
Evans, AR, Euteneuer, S, Chavez, E, Mullen, LM, Hui, EE, Bhatia, SN, and Ryan, AF (2007): Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in an in vitro alternate choice assay. Developmental Neurobiology, 67(13): 1721-1730. (PDF)
Derfus, AM, Chen, AA, Min, D-H, Ruoslahti, E, Bhatia, SN (2007): Targeted quantum dot conjugates for siRNA delivery. Bioconjugate Chemistry, 18(5); 1391-1396 (PDF)
Higgins JM, Eddington DT, Bhatia S, Mahadevan L (2007). Sickle-cell vasoocclusion and rescue in a microfluidic device. PNAS, 104 (51): 20496-20500. (PDF)
Derfus, AM, von Maltzahn, G, Harris, TJ, Duza, T, Vecchio, KS, Ruoslahti, E, Bhatia, SN (2007). Remotely triggered release from magnetic nanoparticles. Advanced Materials, 19: 3932-3936. (PDF)
von Maltzahn, G, Harris, TJ, Park, J-H, Schmidt, AJ, Sailor, MJ, and Bhatia, SN (2007). Nanoparticle self-assembly gated by logical proteolytic triggers. Journal of the American Chemical Society, 129: 6064-6065. (PDF)
Hui, EE and Bhatia, SN (2007). Micromechanical control of cell-cell interactions. PNAS, 104: 5722-5726. (PDF)
Hui, EE and Bhatia, SN (2007). Microscale control of cell contact and spacing via three-component surface patterning. Langmuir, 23: 4103-4107. (PDF)
Simberg, D, Duza, T, Park, J-H, Essler, M, Pilch, J, Zhang, L, Derfus, AM, Yang, M, Hoffman, RM, Bhatia, SN, Sailor, MJ and Ruoslahti1, E (2007). Biomimetic amplification of nanoparticle homing to tumors. PNAS, 104: 932-936. (PDF)
Liu Tsang, V, Chen, AA, Cho, LM, Jadin, KD, Sah, RL, DeLong, S, West, JL, and Bhatia, SN (2007) Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels. FASEB Journal, 21: 790-801. (PDF)
Underhill, GH, Chen, AA, Albrecht, DR, Bhatia, SN (2007). Assessment of hepatocellular function within PEG hydrogels. Biomaterials, 28: 256-270. (PDF)
2000
Behnia K, Bhatia SN, Jastromb N, Balis U, Sullivan S, Yarmush M, and Toner M (2000): Xenobiotic Metabolism by Cultured Primary Porcine Hepatocytes. Tissue Engineering 6(5): 467-479 (PDF)
1999
Bhatia SN, and Chen C (1999): Tissue Engineering at the Micro-Scale. Biomedical Microdevices 2(2): 131-144 (PDF)
Bhatia SN, Balis U, Yarmush ML, and Toner M (1999): Effect of Cell-Cell Interactions in Preservation of Cellular Phenotype: Co-Cultivation of Hepatocytes and Non-Parenchymal Cells. FASEB J 13(14): 1883-1900 (PDF)
Bhatia SN, Suri V, Budny A, and Krauss C (1999): Prenatal detection and mapping of a distal 8p deletion associated with congenital heart disease. Prenatal Diagnosis 19(9): 863-7 (PDF)
Balis UJ, Behnia K, Dwarkanath B, Bhatia SN, Sullivan SJ, Yarmush ML, and Toner M (1999): Oxygen Consumption Characteristics of Porcine Hepatocytes. Metabolic Engineering 1: 49-62 (PDF)
Ledezma GA, Folch A, Bhatia SN, Balis UJ, Yarmush ML, and Toner M (1999): Numerical Model of Fluid Flow and Oxygen Transport in a Radial-Flow Microchannel Containing Hepatocytes. Journal of Biomechanical Engineering 121: 58-64
1998
Bhatia SN, Balis U, Yarmush ML, and Toner M (1998): Probing Heterotypic Cell Interactions: Hepatocyte Function in Microfabricated Co-Cultures. J Biomaterials Science, Polymer Edition 9(11): 1137-1160 (PDF)
Bhatia SN, Balis U, Yarmush ML, and Toner M (1998): Microfabrication of Hepatocyte/Fibroblast Co-Cultures: Role of Homotypic Cell Interactions. Biotechnology Progress 14: 378-387 (PDF)
1997
Bhatia SN, Yarmush ML, and Toner M (1997): Engineered Substrates for Controlling Cell-Cell Interactions. 1997 Advances in Heat and Mass Transfer in Biotechnology ASME HTD-355, BED- 37: 99-103 (PDF)
Bhatia SN, Yarmush ML, and Toner M (1997): Controlling Cell Interactions by Micropatterning in Co-Cultures: Hepatocytes and 3T3 Fibroblasts. Journal of Biomedical Materials Research, 34 (2): 189-199 (PDF)
1996
Bhatia SN, Toner M, Foy BD, Rotem A, O'Neil KM, Tompkins RG, and Yarmush ML (1996): Zonal Liver Cell Heterogeneity: Effects of Oxygen on Metabolic Functions of Hepatocytes. Journal of Cellular Engineering, 1:125-135
1994
Bhatia SN, Toner M, Tompkins RG, and Yarmush ML (1994): Selective Adhesion of Hepatocytes on Patterned Surfaces. Annals of New York Academy of Sciences 745:187-209
Rotem A, Toner M, Bhatia SN, Foy BD, Tompkins RG, and Yarmush ML (1994): Oxygen is a Factor Determining In Vitro Tissue Assembly: Effects on Attachment and Spreading of Hepatocytes. Biotechnology & Bioengineering 43:654-660 (PDF)
2009
Park, J-H, von Maltzahn, G, Zhang, L, Derfus, AM, Simberg, D, Harris, TJ, Ruoslahti, E, Bhatia, SN, and Sailor, MJ (2009 in press): Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting. Small.
Higgins , J, Eddington, D , Bhatia, SN, Mahadevan, L (2009, in press): Statistical dynamics of flowing red blood cells by morphological image processing. PLoS Computational Biology.
Chen, AA[†], Khetani, SR[†], Lee, S, Bhatia, SN, Van Vliet, KJ (2009, in press): Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers. Biomaterials 30: 1113-1120. (PDF)
[†] These authors contributed equally
2008
Alvarez SD, Derfus, AM, Schwartz MP, Bhatia, SN, Sailor, MJ (2008): The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors. Biomaterials, 30: 26-34. (PDF)
Khetani, SR, Chen, AA, Ranscht, B,and Bhatia, SN(2008): T-cadherin modulates hepatocyte functions in vitro. FASEB Journal, 22:3678-3775. (PDF)
Park, J-H, von Maltzahn, G, Ruoslahti, E, Bhatia, SN, Sailor, MJ (2008): Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery. Angewandte Chemie,47: 7284-7288. (PDF)
Von Maltzahn, G, Ren, Y, Bhatia, SN (2008): In vivo tumor cell targeting with "click" nanoparticles. Bioconjugate Chemistry, 19:1570-1578. (PDF)
Harris, TJ, von Maltzahn, G, Lord, ME, Park, J-H, Agrawal, A, Min, D-H, Sailor, MJ, Bhatia, SN (2008): Protease-Triggered Unveiling of Bioactive Nanoparticles. Small, 4:1307-1312. (PDF)
Park, J-H, von Maltzahn, G, Schwartz, MP, Ruoslahti, E, Bhatia, SN, Sailor, MJ (2008, in press): Magnetic iron oxide nanoworms for tumor targeting and imaging. Advanced Materials. (PDF)
News article in Analytical Chemistry 'Analytical Currents' section: Improved superparamagnetic nanoparticles for targeting and imaging; Analytical Chemistry, July 1 2008, page 4777.(PDF)
Flaim CJ, Teng D, Chien S, and Bhatia, SN (2008). Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells and Development, 17: 1–11. (PDF)
Khetani, SR, and Bhatia, SN (2008): Microscale human liver tissue for drug development. Nature Biotechnology, 26 (1): 120-126. (PDF)
2007
Albrecht, DR, Underhill, GH, Mendelson, A, Bhatia, SN (2007). Multiphase electropatterning of cells and biomaterials. Lab on a Chip, 7: 702 – 709. (PDF)
von Maltzahn, G [†], Min, D-H [†], Zhang, Y, Park, J-H, Harris, TJ, Sailor, M, Bhatia, SN (2007): Nanoparticle self-assembly directed by antagonistic kinase and phosphatase activities. Advanced Materials, 19(21): 3579-3583. [†] These authors contributed equally
(PDF)
Underhill, GH and Bhatia, SN (2007): High-throughput analysis of signals regulating stem cell fate and function. Current Opinion in Chemical Biology, 11: 357-366 (PDF)
Evans, AR, Euteneuer, S, Chavez, E, Mullen, LM, Hui, EE, Bhatia, SN, and Ryan, AF (2007): Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in an in vitro alternate choice assay. Developmental Neurobiology, 67(13): 1721-1730. (PDF)
Derfus, AM, Chen, AA, Min, D-H, Ruoslahti, E, Bhatia, SN (2007): Targeted quantum dot conjugates for siRNA delivery. Bioconjugate Chemistry, 18(5); 1391-1396 (PDF)
Higgins JM, Eddington DT, Bhatia S, Mahadevan L (2007). Sickle-cell vasoocclusion and rescue in a microfluidic device. PNAS, 104 (51): 20496-20500. (PDF)
Derfus, AM, von Maltzahn, G, Harris, TJ, Duza, T, Vecchio, KS, Ruoslahti, E, Bhatia, SN (2007). Remotely triggered release from magnetic nanoparticles. Advanced Materials, 19: 3932-3936. (PDF)
von Maltzahn, G, Harris, TJ, Park, J-H, Schmidt, AJ, Sailor, MJ, and Bhatia, SN (2007). Nanoparticle self-assembly gated by logical proteolytic triggers. Journal of the American Chemical Society, 129: 6064-6065. (PDF)
Hui, EE and Bhatia, SN (2007). Micromechanical control of cell-cell interactions. PNAS, 104: 5722-5726. (PDF)
Hui, EE and Bhatia, SN (2007). Microscale control of cell contact and spacing via three-component surface patterning. Langmuir, 23: 4103-4107. (PDF)
Simberg, D, Duza, T, Park, J-H, Essler, M, Pilch, J, Zhang, L, Derfus, AM, Yang, M, Hoffman, RM, Bhatia, SN, Sailor, MJ and Ruoslahti1, E (2007). Biomimetic amplification of nanoparticle homing to tumors. PNAS, 104: 932-936. (PDF)
Liu Tsang, V, Chen, AA, Cho, LM, Jadin, KD, Sah, RL, DeLong, S, West, JL, and Bhatia, SN (2007) Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels. FASEB Journal, 21: 790-801. (PDF)
Underhill, GH, Chen, AA, Albrecht, DR, Bhatia, SN (2007). Assessment of hepatocellular function within PEG hydrogels. Biomaterials, 28: 256-270. (PDF)
2006
Khetani, S.R., and Bhatia, S.N. (2006) Engineering tissues for in vitro applications. Current Opinion in Biotechnology, 17: 524-531. (PDF)
Allen, JW, Khetani, SR, Johnson, RS, and Bhatia, SN. (2006) In vitro liver tissue model established from transgenic mice: Role of HIF-1alpha on hypoxic gene expression. Tissue Engineering, 12 (11): 3135-3147 (PDF)
Park J-H, Derfus AM, Segal E, Vecchio KS, Bhatia SN, Sailor MJ (2006): Local heating of discrete droplets using magnetic porous silicon-based photonic crystals. Journal of the American Chemical Society, 128(24): 7938-7946. (PDF)
Schwartz MP, Derfus AM, Alvarez SD, Bhatia SN, and Sailor MJ (2006): The smart petri dish: A nanostructured photonic crystal for real-time monitoring of living cells. Langmuir, 22: 7084-7090. (PDF)
Albrecht, DR, Underhill, GH, Wassermann, TB, Sah, RL, Bhatia, SN (2006): Probing the role of multicellular organization in 3D microenvironments. Nature Methods, 3: 369-375 (PDF)
Harris TJ, von Maltzahn, G, Derfus AM, Rouslahti E, Bhatia SN (2006): Proteolytic Actuation of Nanoparticle Self-Assembly. Agnewandte Chemie International Edition, 41(19): 3161-3165 (PDF)
Liu, V.A.. and Bhatia, S.N. (2006): 3-D Scaffold Fabrication: Application to Hepatic Tissue Engineering, in Scaffolding in Tissue Engineering. PX Ma and J. Elisseeff, eds., Marcel Dekker, 609-620. (PDF)
Allen, JW, Khetani, SR, Johnson, RS, and Bhatia, SN. (2006) In vitro liver tissue model established from transgenic mice: Role of HIF-1alpha on hypoxic gene expression. Tissue Engineering, 12 (11): 3135-3147 (PDF)
Park J-H, Derfus AM, Segal E, Vecchio KS, Bhatia SN, Sailor MJ (2006): Local heating of discrete droplets using magnetic porous silicon-based photonic crystals. Journal of the American Chemical Society, 128(24): 7938-7946. (PDF)
Schwartz MP, Derfus AM, Alvarez SD, Bhatia SN, and Sailor MJ (2006): The smart petri dish: A nanostructured photonic crystal for real-time monitoring of living cells. Langmuir, 22: 7084-7090. (PDF)
Albrecht, DR, Underhill, GH, Wassermann, TB, Sah, RL, Bhatia, SN (2006): Probing the role of multicellular organization in 3D microenvironments. Nature Methods, 3: 369-375 (PDF)
Harris TJ, von Maltzahn, G, Derfus AM, Rouslahti E, Bhatia SN (2006): Proteolytic Actuation of Nanoparticle Self-Assembly. Agnewandte Chemie International Edition, 41(19): 3161-3165 (PDF)
Liu, V.A.. and Bhatia, S.N. (2006): 3-D Scaffold Fabrication: Application to Hepatic Tissue Engineering, in Scaffolding in Tissue Engineering. PX Ma and J. Elisseeff, eds., Marcel Dekker, 609-620. (PDF)
2005
Chen, AA, Derfus, AM, Khetani, SR, Bhatia, SN (2005): Quantum Dots to Monitor RNAi Delivery and Improve Gene Silencing. Nucleic Acids Research, 33 (22): e190 (PDF)
Flaim, C., Chien, S, Bhatia, S.N. (2005): An Extracellular Matrix Microarray for Probing Cellular Differentiation. Nature Methods 2(2): 119-125 (PDF)
Allen, JW, Khetani, SR, Bhatia, SN (2005): In Vitro Zonation and Toxicity in a Hepatocyte Bioreactor. Toxicological Sciences 84: 110-119 (PDF)
Allen JW, Johnson RS, Bhatia SN. (2005): Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha . Toxicology Letters 155: 151–159 (PDF)
Albrecht, D.R., V.Liu Tsang, Sah, R.L. and Bhatia, S.N. (2005): Photo-and Electropatterning of Live Cellular Arrays Within Hydrogels. Lab on a Chip 5(1):111-118 (PDF)
Flaim, C., Chien, S, Bhatia, S.N. (2005): An Extracellular Matrix Microarray for Probing Cellular Differentiation. Nature Methods 2(2): 119-125 (PDF)
Allen, JW, Khetani, SR, Bhatia, SN (2005): In Vitro Zonation and Toxicity in a Hepatocyte Bioreactor. Toxicological Sciences 84: 110-119 (PDF)
Allen JW, Johnson RS, Bhatia SN. (2005): Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha . Toxicology Letters 155: 151–159 (PDF)
Albrecht, D.R., V.Liu Tsang, Sah, R.L. and Bhatia, S.N. (2005): Photo-and Electropatterning of Live Cellular Arrays Within Hydrogels. Lab on a Chip 5(1):111-118 (PDF)
2004
Dorvee J, Derfus AM, Bhatia SN, Sailor MJ. (2004) Manipulation of Liquid Droplets using Amphiphilic, Magnetic 1-D Photonic Crystal Chaperones." Nature Materials 3: 896 - 899 (PDF)
Chin V Sanga S, Taupin P, Scheel J, Gage FG, Bhatia SN (2004): A Microfabricated Platform for Studying Stem Cell Fates. Biotechnology and Bioengineering 88(3): 399-415 (PDF)
Albrecht D. Sah R, Bhatia SN (2004): Geometric and Material Determinants of Patterning Efficiency by Dielectrophoresis. Biophysical Journal 87(4): 2131-2147 (PDF)
Liu V, Bhatia SN (2004): 3D Tissue Fabrication. Advanced Drug Delivery 56: 1635-1647 (PDF)
Bhatia SN (2004), "Cell and Tissue-Based Sensors", WTEC (World Technology Evaluation Center) Panel Report on International Research and Development in Biosensing, 35-42
Khetani S, Szulgit G, Del Rio J, Barlow C, Bhatia SN (2004): Exploring Mechanisms Of Stromal-Epithelial Cell Interactions Using Gene Expression Profiling. Hepatology 40(3): 545-554 (PDF)
Derfus A, Chan W, Bhatia SN (2004): Intracellular Delivery of Quantum Dots for Live Cell Labeling and Organelle Tracking. Advanced Materials 16(12): 961-966. (PDF)
Derfus A, Chan W, Bhatia SN (2004): Probing the Cytotoxicity of Semiconductor Quantum Dots. Nanoletters 4(1): 11-18 (PDF)
Lin P, Chan W, Badylak S, Bhatia SN (2004): Assessing Liver-Derived Biomatrix for Hepatic Tissue Engineering. Tissue Engineering 10 (7/8): 1046-1053 (PDF)
Chin V Sanga S, Taupin P, Scheel J, Gage FG, Bhatia SN (2004): A Microfabricated Platform for Studying Stem Cell Fates. Biotechnology and Bioengineering 88(3): 399-415 (PDF)
Albrecht D. Sah R, Bhatia SN (2004): Geometric and Material Determinants of Patterning Efficiency by Dielectrophoresis. Biophysical Journal 87(4): 2131-2147 (PDF)
Liu V, Bhatia SN (2004): 3D Tissue Fabrication. Advanced Drug Delivery 56: 1635-1647 (PDF)
Bhatia SN (2004), "Cell and Tissue-Based Sensors", WTEC (World Technology Evaluation Center) Panel Report on International Research and Development in Biosensing, 35-42
Khetani S, Szulgit G, Del Rio J, Barlow C, Bhatia SN (2004): Exploring Mechanisms Of Stromal-Epithelial Cell Interactions Using Gene Expression Profiling. Hepatology 40(3): 545-554 (PDF)
Derfus A, Chan W, Bhatia SN (2004): Intracellular Delivery of Quantum Dots for Live Cell Labeling and Organelle Tracking. Advanced Materials 16(12): 961-966. (PDF)
Derfus A, Chan W, Bhatia SN (2004): Probing the Cytotoxicity of Semiconductor Quantum Dots. Nanoletters 4(1): 11-18 (PDF)
Lin P, Chan W, Badylak S, Bhatia SN (2004): Assessing Liver-Derived Biomatrix for Hepatic Tissue Engineering. Tissue Engineering 10 (7/8): 1046-1053 (PDF)
2003
Li YY, Cunin F, Link JR, Gao T, Betts RE, Reiver SH, Chin V, Bhatia SN, Sailor MJ (2003): Polymer Replicas of Photonic Porous Silicon For Sensing and Drug Delivery Applications. Science 299: 2045-2047 (PDF)
Gopalan SM, Flaim C, Bhatia SN, Hoshijima M, Knoel R, Chien KR, Omens JH, and McCulloch AD (2003): Anisotropic Stretch-induced Hypertrophy in Neonatal Ventricular Myocytes Micropatterned on Deformable Elastomers. Biotechnology & Bioengineering 81(5): 578-587 (PDF)
Allen J W, and Bhatia SN (2003) Formation of Steady-State Oxygen Gradients In vitro: Application to Liver Zonation. Biotechnology and Bioengineering 82: 253-262 (PDF)
Ozkan M, Pisanic T, Barlow C, Esener, S, and Bhatia SN (2003): An Integrated Electro-Optical Platform for the Manipulation of Live Cells. Langmuir 19: 1532-1538 (PDF)
Vozzi G, Flaim CJ, Ahluwalia A, and Bhatia SN (2003): Fabrication of PLGA Scaffolds Using Soft Lithography and Microsyringe Deposition. Biomaterials 24: 2533-2540 (PDF)
Gopalan SM, Flaim C, Bhatia SN, Hoshijima M, Knoel R, Chien KR, Omens JH, and McCulloch AD (2003): Anisotropic Stretch-induced Hypertrophy in Neonatal Ventricular Myocytes Micropatterned on Deformable Elastomers. Biotechnology & Bioengineering 81(5): 578-587 (PDF)
Allen J W, and Bhatia SN (2003) Formation of Steady-State Oxygen Gradients In vitro: Application to Liver Zonation. Biotechnology and Bioengineering 82: 253-262 (PDF)
Ozkan M, Pisanic T, Barlow C, Esener, S, and Bhatia SN (2003): An Integrated Electro-Optical Platform for the Manipulation of Live Cells. Langmuir 19: 1532-1538 (PDF)
Vozzi G, Flaim CJ, Ahluwalia A, and Bhatia SN (2003): Fabrication of PLGA Scaffolds Using Soft Lithography and Microsyringe Deposition. Biomaterials 24: 2533-2540 (PDF)
2002
Liu, V.A. and Bhatia, SN(2002): Three-Dimensional Photopatterning of Hydrogels Containing Living Cells. Biomedical Microdevices 4(4): 257-66 (PDF)
Akerman ME*, Chan WCW*, Laakkonen P, Bhatia SN and Ruoslahti E (2002): Nanocrystal Targeting In Vivo. PNAS 99(20): 12617-12621 *These authors contributed equally. (PDF)
Cunin F, Schmedake TA, Link JR, Koh, J, Bhatia SN and Sailor MJ (2002): Biomolecular screening with encoded porous silicon photonic crystals. Nature Materials 1(1): 39-41 (PDF)
Allen J W, and Bhatia SN (2002) Improving the Next Generation of Bioartificial Liver Devices. Seminars in Cell and Developmental Biology 13(6): 447-454 (PDF)
Allen J, Hassenein T, and Bhatia SN (2002): Engineering Liver Therapies for the Future. Tissue Engineering, 8(5): 725-737 (PDF)
Ozkan M, Bhatia SN, and Esener, SC (2002): Optical Addressing of Polymer Beads in Microdevices. Sensors and Materials, 14(4): 189-97 (PDF)
Heyman GD, Bryn M, and Bhatia SN (2002): Gender and Achievement-Related Beliefs among Engineering Students: A Social-Cognitive Perspective. The Journal of Women and Minorities in Science and Engineering 8 (1): 41-52 (PDF)
Vozzi G, Flaim CJ, Ahluwalia A, Bianchi F, and Bhatia SN (2002): Microfabricated PLGA Scaffolds: A Comparative Study for Application to Tissue Engineering. Materials Science & Engineering C, 20(1-2): 43-47 (PDF)
Liu VA, Jastromb WE, and Bhatia SN (2002): Engineering protein and cell adhesivity using PEO-terminated triblock polymers. Journal of Biomedical Materials Research 60(1): 126-134 (PDF)
Akerman ME*, Chan WCW*, Laakkonen P, Bhatia SN and Ruoslahti E (2002): Nanocrystal Targeting In Vivo. PNAS 99(20): 12617-12621 *These authors contributed equally. (PDF)
Cunin F, Schmedake TA, Link JR, Koh, J, Bhatia SN and Sailor MJ (2002): Biomolecular screening with encoded porous silicon photonic crystals. Nature Materials 1(1): 39-41 (PDF)
Allen J W, and Bhatia SN (2002) Improving the Next Generation of Bioartificial Liver Devices. Seminars in Cell and Developmental Biology 13(6): 447-454 (PDF)
Allen J, Hassenein T, and Bhatia SN (2002): Engineering Liver Therapies for the Future. Tissue Engineering, 8(5): 725-737 (PDF)
Ozkan M, Bhatia SN, and Esener, SC (2002): Optical Addressing of Polymer Beads in Microdevices. Sensors and Materials, 14(4): 189-97 (PDF)
Heyman GD, Bryn M, and Bhatia SN (2002): Gender and Achievement-Related Beliefs among Engineering Students: A Social-Cognitive Perspective. The Journal of Women and Minorities in Science and Engineering 8 (1): 41-52 (PDF)
Vozzi G, Flaim CJ, Ahluwalia A, Bianchi F, and Bhatia SN (2002): Microfabricated PLGA Scaffolds: A Comparative Study for Application to Tissue Engineering. Materials Science & Engineering C, 20(1-2): 43-47 (PDF)
Liu VA, Jastromb WE, and Bhatia SN (2002): Engineering protein and cell adhesivity using PEO-terminated triblock polymers. Journal of Biomedical Materials Research 60(1): 126-134 (PDF)
2001
Ozkan M, Ozkan CS, Kibar O, Wang MM, Bhatia SN, and Esener SC (2001): Heterogeneous Integration through Electrokinetic Migration: IEEE Journal of EMB Magazine, 20(6): 144-151 (PDF)
Ozkan M, Esener SC, and Bhatia SN (2001): Electrokinetic Assembly of Microsphere and Cellular Arrays. Materials Research Society Joint Proceedings: Biomaterials for Drug Delivery and Tissue Engineering 662 NN6.4 (PDF)
Chin V, Collins B, Sailor M, and Bhatia SN (2001): Compatibility of Primary Hepatocytes on Nanoporous Silicon. Advanced Materials 13(24): 1877-1880 (PDF)
Allen J, Hassenein T, and Bhatia SN (2001): Advances in Bioartificial Liver Devices. Hepatology 34(3): 447-455 (PDF)
Song L, Bhatia SN, Hu YL, Shiu YT, Li YS, Usami S, and Chien S (2001): Effects of Morphological Patterning on Endothelial Cell Migration. Biorheology 38: 101-108 (PDF)
Ozkan M, Esener SC, and Bhatia SN (2001): Electrokinetic Assembly of Microsphere and Cellular Arrays. Materials Research Society Joint Proceedings: Biomaterials for Drug Delivery and Tissue Engineering 662 NN6.4 (PDF)
Chin V, Collins B, Sailor M, and Bhatia SN (2001): Compatibility of Primary Hepatocytes on Nanoporous Silicon. Advanced Materials 13(24): 1877-1880 (PDF)
Allen J, Hassenein T, and Bhatia SN (2001): Advances in Bioartificial Liver Devices. Hepatology 34(3): 447-455 (PDF)
Song L, Bhatia SN, Hu YL, Shiu YT, Li YS, Usami S, and Chien S (2001): Effects of Morphological Patterning on Endothelial Cell Migration. Biorheology 38: 101-108 (PDF)
1994 - 2000
2000
Behnia K, Bhatia SN, Jastromb N, Balis U, Sullivan S, Yarmush M, and Toner M (2000): Xenobiotic Metabolism by Cultured Primary Porcine Hepatocytes. Tissue Engineering 6(5): 467-479 (PDF)
1999
Bhatia SN, and Chen C (1999): Tissue Engineering at the Micro-Scale. Biomedical Microdevices 2(2): 131-144 (PDF)
Bhatia SN, Balis U, Yarmush ML, and Toner M (1999): Effect of Cell-Cell Interactions in Preservation of Cellular Phenotype: Co-Cultivation of Hepatocytes and Non-Parenchymal Cells. FASEB J 13(14): 1883-1900 (PDF)
Bhatia SN, Suri V, Budny A, and Krauss C (1999): Prenatal detection and mapping of a distal 8p deletion associated with congenital heart disease. Prenatal Diagnosis 19(9): 863-7 (PDF)
Balis UJ, Behnia K, Dwarkanath B, Bhatia SN, Sullivan SJ, Yarmush ML, and Toner M (1999): Oxygen Consumption Characteristics of Porcine Hepatocytes. Metabolic Engineering 1: 49-62 (PDF)
Ledezma GA, Folch A, Bhatia SN, Balis UJ, Yarmush ML, and Toner M (1999): Numerical Model of Fluid Flow and Oxygen Transport in a Radial-Flow Microchannel Containing Hepatocytes. Journal of Biomechanical Engineering 121: 58-64
1998
Bhatia SN, Balis U, Yarmush ML, and Toner M (1998): Probing Heterotypic Cell Interactions: Hepatocyte Function in Microfabricated Co-Cultures. J Biomaterials Science, Polymer Edition 9(11): 1137-1160 (PDF)
Bhatia SN, Balis U, Yarmush ML, and Toner M (1998): Microfabrication of Hepatocyte/Fibroblast Co-Cultures: Role of Homotypic Cell Interactions. Biotechnology Progress 14: 378-387 (PDF)
1997
Bhatia SN, Yarmush ML, and Toner M (1997): Engineered Substrates for Controlling Cell-Cell Interactions. 1997 Advances in Heat and Mass Transfer in Biotechnology ASME HTD-355, BED- 37: 99-103 (PDF)
Bhatia SN, Yarmush ML, and Toner M (1997): Controlling Cell Interactions by Micropatterning in Co-Cultures: Hepatocytes and 3T3 Fibroblasts. Journal of Biomedical Materials Research, 34 (2): 189-199 (PDF)
1996
Bhatia SN, Toner M, Foy BD, Rotem A, O'Neil KM, Tompkins RG, and Yarmush ML (1996): Zonal Liver Cell Heterogeneity: Effects of Oxygen on Metabolic Functions of Hepatocytes. Journal of Cellular Engineering, 1:125-135
1994
Bhatia SN, Toner M, Tompkins RG, and Yarmush ML (1994): Selective Adhesion of Hepatocytes on Patterned Surfaces. Annals of New York Academy of Sciences 745:187-209
Rotem A, Toner M, Bhatia SN, Foy BD, Tompkins RG, and Yarmush ML (1994): Oxygen is a Factor Determining In Vitro Tissue Assembly: Effects on Attachment and Spreading of Hepatocytes. Biotechnology & Bioengineering 43:654-660 (PDF)